*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : GZ4385000
CHEMICAL NAME           : Cyclotetrasiloxane,
                          2,4-diphenyl-2,4,6,6,8,8-hexamethyl-, (E)-
CAS REGISTRY NUMBER     : 35964-61-5
LAST UPDATED            : 198910
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C18-H28-O4-Si4
MOLECULAR WEIGHT        : 420.82
WISWESSER LINE NOTATION : T8-SI-O-SI-O-SI-O-SI-OJ A1 A1 C1 C1 E1 ER& G1 GR
COMPOUND DESCRIPTOR     : Reproductive Effector
SYNONYMS/TRADE NAMES :
   * trans-2,4-Diphenyl-2,4,6,6,8,8-hexamethylcyclotetrasiloxane
 
                       *** HEALTH HAZARD DATA ***
 
                          ** REPRODUCTIVE DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 700 mg/kg
SEX/DURATION            : male 7 day(s) pre-mating
TOXIC EFFECTS :
   Reproductive - Paternal Effects - prostate, seminal vesicle, Cowper's gland,
   accessory glands
REFERENCE :
   TXAPA9 Toxicology and Applied Pharmacology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1959-  Volume(issue)/page/year:
   21,55,1972
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE                    : 2100 mg/kg
SEX/DURATION            : male 21 day(s) pre-mating
TOXIC EFFECTS :
   Reproductive - Paternal Effects - prostate, seminal vesicle, Cowper's gland,
   accessory glands
REFERENCE :
   TXAPA9 Toxicology and Applied Pharmacology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1959-  Volume(issue)/page/year:
   21,55,1972
 
                            *** END OF RECORD ***