*** CHEMICAL IDENTIFICATION ***
RTECS NUMBER : GZ0592800
CHEMICAL NAME : 5H-Cyclopropa(3,4)benz(1,2-e)azulen-5-one,
1,1a-alpha,1b-beta,4,4a,7a-alpha,7b,8,9,9a-
decahydro-3-(hydroxymethyl)-1,1,6,8-alpha-tetramethyl
-4a-beta,7b-alpha,9a- alpha-trihydroxy-,
9a-(2-methylbutyrate)
CAS REGISTRY NUMBER : 28152-97-8
LAST UPDATED : 198609
DATA ITEMS CITED : 3
MOLECULAR FORMULA : C25-H36-O6
MOLECULAR WEIGHT : 432.61
WISWESSER LINE NOTATION : L E3 B675 MV IU NUTJ BQ C1 EOVY2&1 F1 F1 J1Q LQ N1
COMPOUND DESCRIPTOR : Natural Product
Primary Irritant
SYNONYMS/TRADE NAMES :
* 12-Deoxy-phorbol-13-alpha-methylbutyrate
* 12-Deoxyphorbol-13-(2-methylbutyrate)
*** HEALTH HAZARD DATA ***
** SKIN/EYE IRRITATION DATA **
TYPE OF TEST : Standard Draize test
ROUTE OF EXPOSURE : Administration onto the skin
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 400 ng/4H
REFERENCE :
APTOA6 Acta Pharmacologica et Toxicologica. (Copenhagen, Denmark) V.1-59,
1945-86. For publisher information, see PHTOEH Volume(issue)/page/year:
37,250,1975
TYPE OF TEST : Standard Draize test
ROUTE OF EXPOSURE : Administration onto the skin
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 1600 ng/24H
REFERENCE :
APTOA6 Acta Pharmacologica et Toxicologica. (Copenhagen, Denmark) V.1-59,
1945-86. For publisher information, see PHTOEH Volume(issue)/page/year:
37,250,1975
TYPE OF TEST : Open irritation test
ROUTE OF EXPOSURE : Administration onto the skin
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 230 ng
REFERENCE :
ARTODN Archives of Toxicology. (Springer-Verlag, Heidelberger Pl. 3, D-1000
Berlin 33, Fed. Rep. Ger.) V.32- 1974- Volume(issue)/page/year:
44,279,1980
*** END OF RECORD ***