*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : GZ0592400
CHEMICAL NAME           : 5H-Cyclopropa(3,4)benz(1,2-e)azulen-5-one,
                          1,1a-alpha,1b-beta,4,4a,7a-alpha,7b,8,9,9a-
                          decahydro-3-(hydroxymethyl)-1,1,6,8-alpha-tetramethyl
                          -4a-beta,7b-alpha,9a- alpha-trihydroxy-,
                          9a-dodecenoate
CAS REGISTRY NUMBER     : 56530-48-4
LAST UPDATED            : 198609
DATA ITEMS CITED        : 3
MOLECULAR FORMULA       : C32-H48-O6
MOLECULAR WEIGHT        : 528.80
WISWESSER LINE NOTATION : L E3 B675 MV IU NUTJ BQ C1 EOV5U6 F1 F1 J1Q LQ N1
COMPOUND DESCRIPTOR     : Natural Product
                          Primary Irritant
SYNONYMS/TRADE NAMES :
   * 12-Deoxy-phorbol-13-dodecenoate
 
                       *** HEALTH HAZARD DATA ***
 
                      ** SKIN/EYE IRRITATION DATA **
 
TYPE OF TEST            : Standard Draize test
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 30 ng/4H
REFERENCE :
   APTOA6 Acta Pharmacologica et Toxicologica.  (Copenhagen, Denmark)  V.1-59,
   1945-86.  For publisher information, see PHTOEH  Volume(issue)/page/year:
   37,250,1975
 
TYPE OF TEST            : Standard Draize test
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 100 ng/24H
REFERENCE :
   APTOA6 Acta Pharmacologica et Toxicologica.  (Copenhagen, Denmark)  V.1-59,
   1945-86.  For publisher information, see PHTOEH  Volume(issue)/page/year:
   37,250,1975
 
TYPE OF TEST            : Open irritation test
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 42 ng
REFERENCE :
   ARTODN Archives of Toxicology.  (Springer-Verlag, Heidelberger Pl. 3, D-1000
   Berlin 33, Fed. Rep. Ger.)  V.32-    1974-  Volume(issue)/page/year:
   44,279,1980
 
                            *** END OF RECORD ***