*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : GY8422150
CHEMICAL NAME           : 4H-Cyclopent(f)oxacyclatridecin-4-one,
                          1,6,7,8,9,11a,12,13,14,14a-decahydro-13-N,N-
                          dimethylglycyl-1-hydroxy-
LAST UPDATED            : 199712
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C20-H31-N-O5
MOLECULAR WEIGHT        : 365.52
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Breflate
   * NSC-656202
 
                       *** HEALTH HAZARD DATA ***
 
                 ** OTHER MULTIPLE DOSE TOXICITY DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Mammal - dog
DOSE/DURATION           : 50400 mg/kg/3D-I
TOXIC EFFECTS :
   Brain and Coverings - other degenerative changes
   Behavioral - altered sleep time (including change in righting reflex)
   Behavioral - convulsions or effect on seizure threshold
REFERENCE :
   FAATDF Fundamental and Applied Toxicology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1981-  Volume(issue)/page/year: 36(1,
   Pt 2),15,1997
 
                            *** END OF RECORD ***