*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : GX1530000
CHEMICAL NAME           : Cyclohexylamine, 4,4'-methylenebis-
CAS REGISTRY NUMBER     : 1761-71-3
BEILSTEIN REFERENCE NO. : 2079179
LAST UPDATED            : 199710
DATA ITEMS CITED        : 6
MOLECULAR FORMULA       : C13-H26-N2
MOLECULAR WEIGHT        : 210.41
SYNONYMS/TRADE NAMES :
   * Bis(p-aminocyclohexyl)methane
   * Bis(4-aminocyclohexyl)methane
   * 1,4-Bis(aminocyclohexyl)methane
   * Cyclohexanamine, 4,4'-methylenebis-
   * Di(p-aminocyclohexyl)methane
   * p,p'-Diaminodicyclohexylmethane
   * 4,4'-Diaminodicyclohexylmethane
   * HLR 4219
   * HLR 4448
   * Methylenebis(4-aminocyclohexane)
   * 4,4'-Methylenebis(cyclohexanamine)
   * 4,4'-Methylenebis(cyclohexylamine)
   * 4,4'-Methylenedicyclohexanamine
   * 4,4'-Methylenedicyclohexaneamine
   * 4,4'-Methylenedicyclohexylamine
   * PACM 20
   * Wandamin HM
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 670 mg/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
   Lungs, Thorax, or Respiration - dyspnea
   Nutritional and Gross Metabolic - weight loss or decreased weight gain
REFERENCE :
   NTIS** National Technical Information Service.  (Springfield, VA 22161)
   Formerly U.S. Clearinghouse for Scientific & Technical Information.
   Volume(issue)/page/year: OTS0571204
 
TYPE OF TEST            : LC50 - Lethal concentration, 50 percent kill
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 400 mg/m3/4H
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J.,
   Prague, Czechoslovakia, Avicenum, 1986  Volume(issue)/page/year: -,481,1986
 
                 ** OTHER MULTIPLE DOSE TOXICITY DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Mammal - dog
DOSE/DURATION           : 20175 mg/kg/1.5Y-I
TOXIC EFFECTS :
   Gastrointestinal - changes in structure or function of salivary glands
   Liver - fatty liver degeneration
   Kidney, Ureter, Bladder - interstitial nephritis
REFERENCE :
   JJATDK JAT, Journal of Applied Toxicology.  (John Wiley & Sons Ltd., Baffins
   Lane, Chichester, W. Sussex PO19 1UD, UK)  V.1-    1981-
   Volume(issue)/page/year: 11,367,1991

                          *** STATUS IN U.S. ***
 
   EPA TSCA Section 8(b) CHEMICAL INVENTORY
   
   EPA TSCA Section 8(d) unpublished health/safety studies
   
   EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JUNE 1998

 
                            *** END OF RECORD ***