*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : GY0781000
CHEMICAL NAME           : 1H-Cyclopenta(b)benzofuran-5-butanoic acid,
                          2,3,3a,8b-tetrahydro-2-hydroxy-1-(3-hydroxy-4-
                          methyl-1-octen-6-ynyl)-
CAS REGISTRY NUMBER     : 88430-50-6
LAST UPDATED            : 199312
DATA ITEMS CITED        : 3
MOLECULAR FORMULA       : C24-H30-O5
MOLECULAR WEIGHT        : 398.54
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Beraprost
   * ML 1229
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 12 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JKXXAF Japanese Kokai Tokyo Koho Patents.  (U.S. Patent and Trademark
   Office, Foreign Patents, Washington, DC 20231)  Volume(issue)/page/year:
   #92-312531
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 7 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JKXXAF Japanese Kokai Tokyo Koho Patents.  (U.S. Patent and Trademark
   Office, Foreign Patents, Washington, DC 20231)  Volume(issue)/page/year:
   #92-312531
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 13 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JKXXAF Japanese Kokai Tokyo Koho Patents.  (U.S. Patent and Trademark
   Office, Foreign Patents, Washington, DC 20231)  Volume(issue)/page/year:
   #92-312531
 
                            *** END OF RECORD ***