*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : GW2110000
CHEMICAL NAME           : Cyclohexanone,
                          2-((1,2,3,4-tetrahydro-2-isoquinolinyl)methyl)-,
                          hydrochloride
LAST UPDATED            : 199109
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C16-H21-N-O.Cl-H
MOLECULAR WEIGHT        : 279.84
WISWESSER LINE NOTATION : T66 CNT&J C1- BL6VTJ &GH
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * NU-622
   * 2-(2-Tetrahydroisoquinolylmethyl)-1-cyclohexanone hydrochloride
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 575 mg/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
   Behavioral - convulsions or effect on seizure threshold
   Gastrointestinal - changes in structure or function of salivary glands
REFERENCE :
   JPETAB Journal of Pharmacology and Experimental Therapeutics.  (Williams &
   Wilkins Co., 428 E. Preston St., Baltimore, MD 21202)  V.1-    1909/10-
   Volume(issue)/page/year: 91,195,1947
 
                            *** END OF RECORD ***