*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : GV8872760
CHEMICAL NAME           : Cyclohexanol,
                          1-(2-(dimethylamino)-1-(4-methoxyphenyl)ethyl)-,
                          hydrochloride
CAS REGISTRY NUMBER     : 99300-78-4
LAST UPDATED            : 199801
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C17-H27-N-O2.Cl-H
MOLECULAR WEIGHT        : 313.91
COMPOUND DESCRIPTOR     : Drug
                          Human
SYNONYMS/TRADE NAMES :
   * Effexor
   * 1-(2-(Dimethylamino)-1-(4-methoxyphenyl)ethyl)cyclohexanol hydrochloride
   * Venlafaxine hydrochloride
   * Wy 45030
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Human - woman
DOSE/DURATION           : 235 mg/kg/12D-I
TOXIC EFFECTS :
   Lungs, Thorax, or Respiration - fibrosis, focal (pneumoconiosis)
   Lungs, Thorax, or Respiration - acute pulmonary edema
   Gastrointestinal - other changes
REFERENCE :
   JATOD3 Journal of Analytical Toxicology.  (Preston Pub. Inc., POB 48312,
   Niles, IL 60648) V.1-    1977-  Volume(issue)/page/year: 20,266,1996
 
                            *** END OF RECORD ***