*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : GU8644000
CHEMICAL NAME           : Cyclohexanecarboxylic acid, 1-(phenylthio)-,
                          3-(dimethylamino)propyl ester, hydrochloride
CAS REGISTRY NUMBER     : 84245-08-9
LAST UPDATED            : 198703
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C18-H27-N-O2-S.Cl-H
MOLECULAR WEIGHT        : 357.98
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 1-(Phenylthio)cyclohexanecarboxylic acid 3-(dimethylamino)propyl ester  
   hydrochloride
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 450 mg/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
   Behavioral - tremor
   Behavioral - ataxia
REFERENCE :
   PJPPAA Polish Journal of Pharmacology and Pharmacy.  (ARS Polona, POB 1001,
   00-068 Warsaw 1, Poland) V.25-    1973-  Volume(issue)/page/year:
   37,551,1985
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 48 mg/kg
TOXIC EFFECTS :
   Behavioral - altered sleep time (including change in righting reflex)
   Behavioral - changes in motor activity (specific assay)
   Behavioral - ataxia
REFERENCE :
   PJPPAA Polish Journal of Pharmacology and Pharmacy.  (ARS Polona, POB 1001,
   00-068 Warsaw 1, Poland) V.25-    1973-  Volume(issue)/page/year:
   37,551,1985
 
                            *** END OF RECORD ***