*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : GU6850000
CHEMICAL NAME           : Cyclohexaneacetic acid, alpha-phenyl-,
                          1-ethyl-3-pyrrolidinyl ester, hydrochloride
CAS REGISTRY NUMBER     : 101564-16-3
LAST UPDATED            : 198606
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C20-H29-N-O2.Cl-H
MOLECULAR WEIGHT        : 351.96
WISWESSER LINE NOTATION : T5NTJ A2 COVYR&- AL6TJ &GH
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * AHR 246
   * alpha-Phenylcyclohexaneacetic acid 1-ethyl-3-pyrrolidinyl ester  
   hydrochloride
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 775 mg/kg
TOXIC EFFECTS :
   Sense Organs and Special Senses (Eye) - mydriasis (pupillary dilation)
   Behavioral - convulsions or effect on seizure threshold
   Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
   JMPCAS Journal of Medicinal and Pharmaceutical Chemistry.  (Washington, DC)
   V.1-5, 1959-62.  For publisher information, see JMCMAR.
   Volume(issue)/page/year: 2,523,1960
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 160 mg/kg
TOXIC EFFECTS :
   Sense Organs and Special Senses (Eye) - mydriasis (pupillary dilation)
   Behavioral - convulsions or effect on seizure threshold
   Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
   JMPCAS Journal of Medicinal and Pharmaceutical Chemistry.  (Washington, DC)
   V.1-5, 1959-62.  For publisher information, see JMCMAR.
   Volume(issue)/page/year: 2,523,1960
 
                            *** END OF RECORD ***