*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : GU6825000
CHEMICAL NAME           : Cyclohexaneacetic acid, alpha-phenyl-,
                          2-(diethylamino)ethyl ester, hydrochloride
CAS REGISTRY NUMBER     : 548-66-3
LAST UPDATED            : 199706
DATA ITEMS CITED        : 4
MOLECULAR FORMULA       : C20-H31-N-O2.Cl-H
MOLECULAR WEIGHT        : 353.98
WISWESSER LINE NOTATION : L6TJ AYR&VO2N2&2 &GH
SYNONYMS/TRADE NAMES :
   * Adiphenine H hydrochloride
   * Benzeneacetic acid, alpha-cyclohexyl-, 2-(diethylamino)ethyl ester,  
   hydrochloride
   * Cycloadiphenine
   * Cycloadiphenine hydrochloride
   * alpha-Cyclohexylbenzeneacetic acid 2-(diethylamino)ethyl ester  
   hydrochloride
   * Cyclohexylphenylacetyldiethylaminoethanol hydrochloride
   * Cyclospasmol (tempelhof)
   * Cyclovegantine
   * 2-(Diethylamino)ethyl alpha-cyclohexylbenzeneacetate
   * 2-Diethylaminoethyl(alpha-phenylcyclohexane)acetate hydrochloride
   * Drofenine hydrochloride
   * Hexahydroadiphenine hydrochloride
   * IT-19
   * alpha-Phenylcyclohexaneacetic acid 2-(diethylamino)ethyl ester  
   hydrochloride
   *   alpha-Phenyl-cyclohexylessigsaeure-2-diaethylamino-aethylester-hydrochlo
     rid
   * Trasentine-6H hydrochloride
   * Trasentine-A hydrochloride
   * Trasentin H
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 3700 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   CKFRAY Ceskoslovenska Farmacie.  (PNS-Ustredni Expedice a Dovoz Tisku,
   Kafkova 19, 160 00 Prague 6, Czechoslovakia)  V.1-    1952-
   Volume(issue)/page/year: 3,238,1954
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1201 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   CKFRAY Ceskoslovenska Farmacie.  (PNS-Ustredni Expedice a Dovoz Tisku,
   Kafkova 19, 160 00 Prague 6, Czechoslovakia)  V.1-    1952-
   Volume(issue)/page/year: 3,238,1954
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 47 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   CKFRAY Ceskoslovenska Farmacie.  (PNS-Ustredni Expedice a Dovoz Tisku,
   Kafkova 19, 160 00 Prague 6, Czechoslovakia)  V.1-    1952-
   Volume(issue)/page/year: 3,238,1954
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Unreported
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1600 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   FATOAO Farmakologiya i Toksikologiya (Moscow).  For English translation, see
   PHTXA6 and RPTOAN. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.2-   
   1939-  Volume(issue)/page/year: 28,37,1965
 
                            *** END OF RECORD ***