*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : GO5661000
CHEMICAL NAME           : Cremophor EL
CAS REGISTRY NUMBER     : 61791-12-6
OTHER CAS REGISTRY NOS. : 8051-35-2
                          58076-69-0
                          60649-23-2
LAST UPDATED            : 199710
DATA ITEMS CITED        : 8
SYNONYMS/TRADE NAMES :
   * Castor oil, ethoxylated
   * Castor oil polyoxyethylene ether
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 6500 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   AASXAP Acta Anaesthesiologica Scandinavica, Supplementum.  (Munksgaard
   International Pub., POB 2148, DK-1016 Copenhagen K, Denmark)  No.1- 1959- 
   Volume(issue)/page/year: 17,21,1965
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Mammal - dog
DOSE/DURATION           : 640 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   AASXAP Acta Anaesthesiologica Scandinavica, Supplementum.  (Munksgaard
   International Pub., POB 2148, DK-1016 Copenhagen K, Denmark)  No.1- 1959- 
   Volume(issue)/page/year: 17,21,1965

         *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***

NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :
   NOHS - National Occupational Hazard Survey (1974)
     NOHS Hazard Code - M2673
       No. of Facilities: 388 (estimated)
       No. of Industries: 10
       No. of Occupations: 19
       No. of Employees: 13371 (estimated)
   
   NOES - National Occupational Exposure Survey (1983)
     NOES Hazard Code - M2673
       No. of Facilities: 895 (estimated)
       No. of Industries: 18
       No. of Occupations: 15
       No. of Employees: 16381 (estimated)
       No. of Female Employees: 4069 (estimated)
   
   NOES - National Occupational Exposure Survey (1983)
     NOES Hazard Code - T2051
       No. of Facilities: 2481 (estimated)
       No. of Industries: 39
       No. of Occupations: 49
       No. of Employees: 63606 (estimated)
       No. of Female Employees: 25006 (estimated)

                          *** STATUS IN U.S. ***
 
   EPA TSCA Section 8(b) CHEMICAL INVENTORY
   
   EPA TSCA Section 8(e) Risk Notification, 8EHQ-0892-8989
   
   EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JUNE 1998

 
                            *** END OF RECORD ***