*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : GN7648500
CHEMICAL NAME           : Coumarin, 4-hydroxy-3-(p-tolyl)-
CAS REGISTRY NUMBER     : 73791-19-2
BEILSTEIN REFERENCE NO. : 1287628
REFERENCE               : 5-18-02-00308 (Beilstein Handbook Reference)
LAST UPDATED            : 199612
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C16-H12-O3
MOLECULAR WEIGHT        : 252.28
WISWESSER LINE NOTATION : T66 BO CVJ EQ DR D1
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 2H-1-Benzopyran-2-one, 4-hydroxy-3-(p-tolyl)-
   * 4-Hydroxy-3-(p-tolyl)-2H-1-benzopyran-2-one
   * 4-Hydroxy-3-(p-tolyl)coumarin
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 250 mg/kg
TOXIC EFFECTS :
   Behavioral - altered sleep time (including change in righting reflex)
   Behavioral - muscle contraction or spasticity
   Lungs, Thorax, or Respiration - respiratory stimulation
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 14,29,1964
 
                            *** END OF RECORD ***