*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : GN6380000
CHEMICAL NAME           : Coumarin, 7-diethylamino-4-methyl-, hydrogen sulfate
CAS REGISTRY NUMBER     : 67210-66-6
LAST UPDATED            : 199701
DATA ITEMS CITED        : 3
MOLECULAR FORMULA       : C14-H17-N-O2.H2-O4-S
MOLECULAR WEIGHT        : 329.40
WISWESSER LINE NOTATION : T66 BOVJ IN2&2 E1 &WSQQ
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 2H-1-Benzopyran-2-one, 7-(diethylamino)-4-methyl-, sulfate (1:1)
   * Coumarin, 7-(diethylamino)-4-methyl-, sulfate (1:1)
   * 7-(Diethylamino)-4-methyl-2H-1-benzopyran-2-one sulfate (1:1)
   * 7-(Diethylamino)-4-methylcoumarin sulfate
   * 7-Diethylamino-4-methylcoumarin sulfuric acid salt
   * Diethyl-4-methyl-7-coumarinylammonium hydrogen sulfate
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 1600 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J.,
   Prague, Czechoslovakia, Avicenum, 1986  Volume(issue)/page/year: -,806,1986
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1780 mg/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
   Behavioral - convulsions or effect on seizure threshold
   Kidney, Ureter, Bladder - hematuria
REFERENCE :
   ESKHA5 Eisei Shikenjo Hokoku.  Bulletin of the Institute of Hygienic
   Sciences.  (Kokuritsu Eisei Shikenjo Kagaku, 18-1 Bushitsu Johobu,
   Setagaya-ku, Tokyo 158, Japan)  V.1-    1886-  Volume(issue)/page/year:
   (104),45,1986

                          *** STATUS IN U.S. ***
 
   EPA TSCA Section 8(b) CHEMICAL INVENTORY

 
                            *** END OF RECORD ***