*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : GN4932800
CHEMICAL NAME           : Coumarin, 6-amino-3-(1-pyrrolidinylcarbonyl)-
CAS REGISTRY NUMBER     : 18144-55-3
LAST UPDATED            : 198408
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C14-H14-N2-O3
MOLECULAR WEIGHT        : 258.30
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 6-Amino-3-(1-pyrrolidinylcarbonyl)coumarin
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 325 mg/kg
TOXIC EFFECTS :
   Behavioral - altered sleep time (including change in righting reflex)
   Behavioral - changes in motor activity (specific assay)
REFERENCE :
   YKKZAJ Yakugaku Zasshi.  Journal of Pharmacy.  (Nippon Yakugakkai, 2-12-15
   Shibuya, Shibuya-ku, Tokyo 150, Japan)  No.1-    1881-
   Volume(issue)/page/year: 88,755,1968
 
                            *** END OF RECORD ***