*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : GN1038000
CHEMICAL NAME           : Corynan-16-carboxylic acid,
                          16,17-didehydro-17-methoxy-, methyl ester, (16E)-
CAS REGISTRY NUMBER     : 50439-68-4
LAST UPDATED            : 198909
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C22-H28-N2-O3
MOLECULAR WEIGHT        : 368.52
COMPOUND DESCRIPTOR     : Drug
                          Natural Product
SYNONYMS/TRADE NAMES :
   * Corynantheine, dihydro-
   * Dihydrocorynantheine
   * 18,19-Dihydrocorynantheine
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 89 mg/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
   Behavioral - convulsions or effect on seizure threshold
   Lungs, Thorax, or Respiration - other changes
REFERENCE :
   NYKZAU Nippon Yakurigaku Zasshi.  Japanese Journal of Pharmacology. (Nippon
   Yakuri Gakkai, c/o Kyoto Daigaku Igakubu Yakurigaku Kyoshitsu, Konoe-cho,
   Yoshida, Sakyo-ku, Kyoto 606, Japan) V.40-    1944- Volume(issue)/page/year:
   94,17,1989
 
                            *** END OF RECORD ***