*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : GH0887000
CHEMICAL NAME           : Colchicine, 17-fluoro-
CAS REGISTRY NUMBER     : 26195-68-6
BEILSTEIN REFERENCE NO. : 2790210
LAST UPDATED            : 199612
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C22-H24-F-N-O6
MOLECULAR WEIGHT        : 417.47
WISWESSER LINE NOTATION : L B677 MV&T&J CO1 DO1 EO1 JMV1F NO1
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Acetamide,  
   2-fluoro-N-(5,6,7,9-tetrahydro-1,2,3,10-tetramethoxy-9-oxobenzo(a)heptal  
   en-7-yl)-
   * 17-Fluorocolchicine
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 852 ug/kg
TOXIC EFFECTS :
   Tumorigenic - active as anti-cancer agent
REFERENCE :
   JMCMAR Journal of Medicinal Chemistry.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
   20037)  V.6-    1963-  Volume(issue)/page/year: 24,636,1981
 
                            *** END OF RECORD ***