*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : GH0885000
CHEMICAL NAME           : Colchicine, 5,6-didehydrodeacetamido-
CAS REGISTRY NUMBER     : 14511-67-2
BEILSTEIN REFERENCE NO. : 2482144
LAST UPDATED            : 199612
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C20-H20-O5
MOLECULAR WEIGHT        : 340.40
WISWESSER LINE NOTATION : L B677 MV JHJ CO1 DO1 EO1 NO1
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Benzo(a)heptalen-9(5H)-one, 1,2,3,10-tetramethoxy-
   * Colchicine, deacetamido-6-dehydro-
   * Deacetamido-6-dehydrocolchicine
   * Deacetamido-5,6-didehydrocolchicine
   * 5,6-Dehydro-7-deacetamidocolchicine
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intramuscular
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 102 mg/kg
TOXIC EFFECTS :
   Nutritional and Gross Metabolic - weight loss or decreased weight gain
REFERENCE :
   JMCMAR Journal of Medicinal Chemistry.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
   20037)  V.6-    1963-  Volume(issue)/page/year: 24,257,1981
 
                            *** END OF RECORD ***