*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : GH0570000
CHEMICAL NAME           : Colchiceine, N-deacetyl-N-benzoyl-
CAS REGISTRY NUMBER     : 14686-58-9
LAST UPDATED            : 199606
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C26-H25-N-O6
MOLECULAR WEIGHT        : 447.52
SYNONYMS/TRADE NAMES :
   * Benzo(a)heptalen-9(5H)-one,  
   7-benzamido-6,7-dihydro-10-hydroxy-1,2,3-trimethoxy-
   * N-Benzoyl trimethylcolchicinic acid
   * Colchiceine, N-benzoyl-N-deacetyl-
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : >700 mg/kg
TOXIC EFFECTS :
   Behavioral - sleep
   Behavioral - somnolence (general depressed activity)
   Lungs, Thorax, or Respiration - respiratory depression
REFERENCE :
   CANCAR Cancer (Philadelphia).  (Lippincott/Harper, Journal Fulfillment
   Dept., 2350 Virginia Ave., Hagerstown, MD 21740)  V.1-    1948-
   Volume(issue)/page/year: 3,124,1950
 
                            *** END OF RECORD ***