*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : GD8450000
CHEMICAL NAME           : Cinnamic acid, o-chloro-
CAS REGISTRY NUMBER     : 3752-25-8
BEILSTEIN REFERENCE NO. : 1365198
REFERENCE               : 0-09-00-00594 (Beilstein Handbook Reference)
LAST UPDATED            : 199612
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C9-H7-Cl-O2
MOLECULAR WEIGHT        : 182.61
WISWESSER LINE NOTATION : QV1U1R BG
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * o-Chlorocinnamic acid
   * 2-Chlorocinnamic acid
   * 3-(2-Chlorophenyl)-2-propenoic acid
   * 2-Propenoic acid, 3-(2-chlorophenyl)-
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 989 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   PHARAT Pharmazie.  (VEB Verlag Volk und Gesundheit, Neue Gruenstr. 18,
   Berlin DDR-1020, Ger. Dem. Rep.)  V.1-    1946-  Volume(issue)/page/year:
   23,714,1968
 
TYPE OF TEST            : LD - Lethal dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : >350 mg/kg
TOXIC EFFECTS :
   Behavioral - changes in motor activity (specific assay)
   Behavioral - ataxia
   Behavioral - rigidity (including catalepsy)
REFERENCE :
   IJSIDW Indian Journal of Pharmaceutical Sciences.  (Kalina, Santa Cruz
   (East), Bombay 400 029, India)  V.40(2)-    1978-  Volume(issue)/page/year:
   49,77,1987
 
                            *** END OF RECORD ***