*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : GB6850000
CHEMICAL NAME           : Chromium(III) potassium sulfate (1:1:2),
                          dodecahydrate
CAS REGISTRY NUMBER     : 7788-99-0
LAST UPDATED            : 199712
DATA ITEMS CITED        : 14
MOLECULAR FORMULA       : O8-S2.Cr.K.12H2-O
MOLECULAR WEIGHT        : 499.41
COMPOUND DESCRIPTOR     : Tumorigen
                          Mutagen
SYNONYMS/TRADE NAMES :
   * Chrome alum (dodecahydrate)
   * Potassium chromium alum dodecahydrate
   * Sulfuric acid, chromium(3+)potassium salt(2:1:1), dodecahydrate
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 112 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   EQSSDX Environmental Quality and Safety, Supplement.  (Stuttgart, Fed. Rep.
   Ger.)  V.1-5, 1975-76. Discontinued.  Volume(issue)/page/year: 1,1,1975
 
                          ** TUMORIGENIC DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 135 mg/kg
TOXIC EFFECTS :
   Tumorigenic - equivocal tumorigenic agent by RTECS criteria
   Tumorigenic - tumors at site of application
REFERENCE :
   PBPHAW Progress in Biochemical Pharmacology.  (S. Karger AG, Postfach
   CH-4009 Basel, Switzerland) V.1-    1965-  Volume(issue)/page/year:
   14,47,1978
 
                            ** MUTATION DATA **
 
TYPE OF TEST            : DNA repair
TEST SYSTEM             : Bacteria - Escherichia coli
DOSE/DURATION           : 125 ug/well
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 133,161,1984

                              *** REVIEWS ***
 
   ACGIH TLV-TWA 0.5 mg(Cr)/m3
   DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices
   (BEIs) booklet issues by American Conference of Governmental Industrial
   Hygienists (ACGIH), Cincinnati, OH, 1996  Volume(issue)/page/year:
   TLV/BEI,1997

   ACGIH TLV-Not classifiable as a human carcinogen
   DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices
   (BEIs) booklet issues by American Conference of Governmental Industrial
   Hygienists (ACGIH), Cincinnati, OH, 1996  Volume(issue)/page/year:
   TLV/BEI,1997

   TOXICOLOGY REVIEW
   85DHAX "Medical and Biologic Effects of Environmental Pollutants Series,"
   Washington, DC, National Academy of Sciences, 1972-77
   Volume(issue)/page/year: Cr,22,1974

                    *** U.S. STANDARDS AND REGULATIONS ***
 
   MSHA STANDARD-air:TWA 1 mg(Cr)/m3
   DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices
   (BEIs) booklet issues by American Conference of Governmental Industrial
   Hygienists (ACGIH), Cincinnati, OH, 1996  Volume(issue)/page/year: 3,35,1971

   OSHA PEL (Gen Indu):8H TWA 0.5 mg(Cr)/m3
   CFRGBR Code of Federal Regulations.  (U.S. Government Printing Office, Supt.
   of Documents, Washington, DC 20402)  Volume(issue)/page/year:
   29,1910.1000,1994

   OSHA PEL (Construc):8H TWA 0.5 mg(Cr)/m3
   CFRGBR Code of Federal Regulations.  (U.S. Government Printing Office, Supt.
   of Documents, Washington, DC 20402)  Volume(issue)/page/year:
   29,1926.55,1994

   OSHA PEL (Shipyard):8H TWA 0.5 mg(Cr)/m3
   CFRGBR Code of Federal Regulations.  (U.S. Government Printing Office, Supt.
   of Documents, Washington, DC 20402)  Volume(issue)/page/year:
   29,1915.1000,1993

   OSHA PEL (Fed Cont):8H TWA 0.5 mg(Cr)/m3
   CFRGBR Code of Federal Regulations.  (U.S. Government Printing Office, Supt.
   of Documents, Washington, DC 20402)  Volume(issue)/page/year:
   41,50-204.50,1994

         *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***

NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :
   NOHS - National Occupational Hazard Survey (1974)
     NOHS Hazard Code - 82893
       No. of Facilities: 26 (estimated)
       No. of Industries: 3
       No. of Occupations: 6
       No. of Employees: 391 (estimated)
   
   NOES - National Occupational Exposure Survey (1983)
     NOES Hazard Code - 82893
       No. of Facilities: 518 (estimated)
       No. of Industries: 7
       No. of Occupations: 6
       No. of Employees: 9625 (estimated)
       No. of Female Employees: 119 (estimated)

                          *** STATUS IN U.S. ***
 
   EPA GENETOX PROGRAM 1988, Inconclusive: Histidine reversion-Ames test

 
                            *** END OF RECORD ***