*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : GD7193000
CHEMICAL NAME           : Cinnamamide, p-chloro-alpha,beta-dimethyl-, (E)-
CAS REGISTRY NUMBER     : 77302-32-0
LAST UPDATED            : 199409
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C11-H12-Cl-N-O
MOLECULAR WEIGHT        : 209.69
WISWESSER LINE NOTATION : ZVY1&UY1&R DG
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 2-Butenamide, 3-(4-chlorophenyl)-2-methyl-, (E)-
   * trans-p-Chloro-alpha,beta-dimethylcinnamamide
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 550 mg/kg
TOXIC EFFECTS :
   Behavioral - anticonvulsant
   Behavioral - altered sleep time (including change in righting reflex)
   Behavioral - changes in motor activity (specific assay)
REFERENCE :
   JMCMAR Journal of Medicinal Chemistry.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
   20037)  V.6-    1963-  Volume(issue)/page/year: 24,525,1981
 
                            *** END OF RECORD ***