*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : GD3418000
CHEMICAL NAME           : Cinchoninamide,
                          N-(2-(diethylamino)ethyl)-2-ethoxy-N-(2,6-xylyl)-,
                          hydrochloride
CAS REGISTRY NUMBER     : 77945-03-0
LAST UPDATED            : 199409
DATA ITEMS CITED        : 3
MOLECULAR FORMULA       : C26-H33-N3-O2.Cl-H
MOLECULAR WEIGHT        : 456.08
WISWESSER LINE NOTATION : T66 BNJ CO2 EVN2N2&2&R B1 F1 &GH
COMPOUND DESCRIPTOR     : Drug
                          Primary Irritant
SYNONYMS/TRADE NAMES :
   * C 3222
   * N-(2-(Diethylamino)ethyl)-2-ethoxy-N-(2,6-xylyl)cinchoninamide  
   hydrochloride
   * N-(2-(Diethylamino)ethyl)-2-ethoxy-N-(2,6-xylyl)-4-quinolinecarboxamide,  
   hydrochloride
   * 4-Quinolinecarboxamide,  
   N-(2-(diethylamino)ethyl)-N-(2,6-dimethylphenyl)-2-epoxy-, HCl
 
                       *** HEALTH HAZARD DATA ***
 
                      ** SKIN/EYE IRRITATION DATA **
 
TYPE OF TEST            : Standard Draize test
ROUTE OF EXPOSURE       : Administration into the eye
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 2%
REACTION SEVERITY       : Severe
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 8,708,1958
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 150 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 8,708,1958
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 250 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 8,708,1958
 
                            *** END OF RECORD ***