*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : GC2653000
CHEMICAL NAME           : Chrysotile, nickel
LAST UPDATED            : 199712
DATA ITEMS CITED        : 3
MOLECULAR FORMULA       : Ni6.O10-Si4.H8-O8
MOLECULAR WEIGHT        : 760.70
COMPOUND DESCRIPTOR     : Tumorigen
SYNONYMS/TRADE NAMES :
   * Nickel chrysotile
 
                       *** HEALTH HAZARD DATA ***
 
                          ** TUMORIGENIC DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intrapleural
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 300 mg/kg/8W-I
TOXIC EFFECTS :
   Tumorigenic - equivocal tumorigenic agent by RTECS criteria
   Skin and Appendages - breast
REFERENCE :
   EKSODD Eksperimental'naya Onkologiya.  Experimental Oncology.  (V/O
   Mezhdunarodnaya Kniga, 113095 Mosow, USSR)  V.1-    1979-
   Volume(issue)/page/year: 11(4),26,1989

                              *** REVIEWS ***
 
   ACGIH TLV-TWA 2 fibers/cc
   DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices
   (BEIs) booklet issues by American Conference of Governmental Industrial
   Hygienists (ACGIH), Cincinnati, OH, 1996  Volume(issue)/page/year:
   TLV/BEI,1997

   ACGIH TLV-Confirmed human carcinogen
   DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices
   (BEIs) booklet issues by American Conference of Governmental Industrial
   Hygienists (ACGIH), Cincinnati, OH, 1996  Volume(issue)/page/year:
   TLV/BEI,1997

 
                            *** END OF RECORD ***