*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : GC2062100
CHEMICAL NAME           : Chryseno(3,4-b)oxirene-1,2-diol,
                          1,2,2a,3a-tetrahydro-4-methyl-,
                          (1-alpha,2-beta,2a-alpha,3a- alpha)-
CAS REGISTRY NUMBER     : 81851-68-5
OTHER CAS REGISTRY NOS. : 97170-06-4
LAST UPDATED            : 199707
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C19-H16-O3
MOLECULAR WEIGHT        : 292.35
COMPOUND DESCRIPTOR     : Tumorigen
                          Mutagen
SYNONYMS/TRADE NAMES :
   * trans-1,2-Dihydroxy-syn-3,4-epoxy-1,2,3,4-tetrahydro-5-methylchrysene
   * anti-5-Methylchrysene-1,2-diol-3,4-epoxide
 
                       *** HEALTH HAZARD DATA ***
 
                          ** TUMORIGENIC DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1403 mg/kg/15D-I
TOXIC EFFECTS :
   Tumorigenic - Carcinogenic by RTECS criteria
   Lungs, Thorax, or Respiration - tumors
   Liver - tumors
REFERENCE :
   CALEDQ Cancer Letters (Shannon, Ireland).  (Elsevier Scientific Pub. Ireland
   Ltd., POB 85, Limerick, Ireland)  V.1-    1975- Volume(issue)/page/year:
   58,115,1991
 
                            ** MUTATION DATA **
 
TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Bacteria - Salmonella typhimurium
DOSE/DURATION           : 400 pmol/plate
REFERENCE :
   CRNGDP Carcinogenesis (London). (Oxford Univ. Press, Pinkhill House,
   Southfield Road, Eynsham, Oxford OX8 1JJ, UK)  V.1-    1980-
   Volume(issue)/page/year: 7,2067,1986
 
                            *** END OF RECORD ***