*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : GC2055000
CHEMICAL NAME           : Chryseno(3,4-b)oxirene-1,2-diol,
                          1,2,2a,3a-tetrahydro-,
                          (1-alpha,2-beta,2a-alpha,3a-alpha)-
CAS REGISTRY NUMBER     : 64938-66-5
LAST UPDATED            : 199410
DATA ITEMS CITED        : 3
MOLECULAR FORMULA       : C18-H14-O3
MOLECULAR WEIGHT        : 278.32
WISWESSER LINE NOTATION : T F6 C6 B663 SO&&&TTJ PQ QQ
COMPOUND DESCRIPTOR     : Tumorigen
                          Mutagen
SYNONYMS/TRADE NAMES :
   * anti-Chrysene-1,2-diol-3,4-epoxide
   * Chrysenediol, 3,4-epoxy-1,2,3,4-tetrahydro-, (+)-(E)-
   * trans-1,2-Dihydroxy-anti-3,4-epoxy-1,2,3,4-tetrahydrochrysene
   * r-1,t-2-Dihydroxy-c-3,4-oxy-1,2,3,4-tetrahydrochrysene
   * (Z)-1,2,2a,3a-Tetrahydrochryseno(3,4-b)oxirene-1,2-diol
   *   1-alpha,2-beta,2a-alpha,3a-alpha-1,2,2a,3a-Tetrahydrochryseno(3,4-b)oxir
     ene-1,2-diol
   *   1-alpha,2-beta,2a-alpha,3a-alpha-Tetrahydrochryseno(3,4-b)oxirene-1,2-di
     ol
 
                       *** HEALTH HAZARD DATA ***
 
                          ** TUMORIGENIC DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 20 mg/kg
TOXIC EFFECTS :
   Tumorigenic - neoplastic by RTECS criteria
   Skin and Appendages - tumors
   Tumorigenic - tumors at site of application
REFERENCE :
   CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut
   Sts., Philadelphia, PA 19106)  V.1-    1941-  Volume(issue)/page/year:
   40,1981,1980
 
                            ** MUTATION DATA **
 
TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Bacteria - Salmonella typhimurium
DOSE/DURATION           : 250 nmol/plate
REFERENCE :
   CRNGDP Carcinogenesis (London). (Oxford Univ. Press, Pinkhill House,
   Southfield Road, Eynsham, Oxford OX8 1JJ, UK)  V.1-    1980-
   Volume(issue)/page/year: 9,2305,1988
 
TYPE OF TEST            : Mutation in mammalian somatic cells
TEST SYSTEM             : Rodent - hamster Liver
DOSE/DURATION           : 5 umol/L
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 271,79,1992
 
                            *** END OF RECORD ***