*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : FZ3620000
CHEMICAL NAME           : Cholanthrene, 6,7,8,9,10,12b-hexahydro-3-methyl-
CAS REGISTRY NUMBER     : 35281-27-7
BEILSTEIN REFERENCE NO. : 2465473
REFERENCE               : 3-10-00-01641 (Beilstein Handbook Reference)
LAST UPDATED            : 199612
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C21-H22
MOLECULAR WEIGHT        : 274.43
WISWESSER LINE NOTATION : L E6 D6656 1A TT&TT&J R1
COMPOUND DESCRIPTOR     : Tumorigen
                          Mutagen
SYNONYMS/TRADE NAMES :
   * Benz(j)aceanthrylene, 1,2,6,7,8,9,10,12b-octahydro-3-methyl-
   * 6,7,8,9,10,12b-Hexahydro-3-methyl-cholanthrene
   * 1,2,6,7,8,9,10,12b-Octahydro-3-methylbenz(j)aceanthrylene
 
                       *** HEALTH HAZARD DATA ***
 
                          ** TUMORIGENIC DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 140 mg/kg/50W-I
TOXIC EFFECTS :
   Tumorigenic - Carcinogenic by RTECS criteria
   Skin and Appendages - tumors
   Tumorigenic - tumors at site of application
REFERENCE :
   ZKKOBW Zeitschrift fuer Krebsforschung und Klinische Onkologie.  (Berlin,
   Fed. Rep. Ger.)  V.76-92, 1971-78.  For publisher information, see JCROD7.
   Volume(issue)/page/year: 77,226,1972
 
                            ** MUTATION DATA **
 
TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Bacteria - Salmonella typhimurium
DOSE/DURATION           : 1 ug/plate
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 51,311,1978
 
                            *** END OF RECORD ***