*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : FZ3325000
CHEMICAL NAME           : Cholanthrene, 11,12-dihydro-3-methyl-
CAS REGISTRY NUMBER     : 25486-92-4
BEILSTEIN REFERENCE NO. : 2133982
REFERENCE               : 3-05-00-02429 (Beilstein Handbook Reference)
LAST UPDATED            : 199612
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C21-H18
MOLECULAR WEIGHT        : 270.39
WISWESSER LINE NOTATION : L E6 D6656 1A T&T&T&J R1
COMPOUND DESCRIPTOR     : Tumorigen
                          Mutagen
SYNONYMS/TRADE NAMES :
   * Benz(j)aceanthrylene, 1,2,11,12-tetrahydro-3-methyl-
   * 11,12-Dihydro-3-methylcholanthrene
 
                       *** HEALTH HAZARD DATA ***
 
                          ** TUMORIGENIC DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 168 mg/kg/57W-I
TOXIC EFFECTS :
   Tumorigenic - equivocal tumorigenic agent by RTECS criteria
   Skin and Appendages - tumors
   Tumorigenic - tumors at site of application
REFERENCE :
   JNCIAM Journal of the National Cancer Institute.  (Washington, DC)  V.1-60,
   1940-78.  For publisher information, see JJIND8.  Volume(issue)/page/year:
   44,641,1970
 
                            ** MUTATION DATA **
 
TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Bacteria - Salmonella typhimurium
DOSE/DURATION           : 25 ug/plate
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 51,311,1978
 
                            *** END OF RECORD ***