*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : FL5760000
CHEMICAL NAME           : Cevane-3-beta,4-beta,6-alpha,7-alpha,14,15-alpha,16-b
                          eta,20-octol, 4,9-epoxy-, 6,7- diacetate,
                          3-((+)-2-hydroxy-2-methylbutyrate)
                          15-((-)-2-methylbutyrate), hydrochloride
CAS REGISTRY NUMBER     : 58445-86-6
LAST UPDATED            : 199009
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C41-H63-N-O14.Cl-H
MOLECULAR WEIGHT        : 830.51
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Protoveratrine A hydrochloride
   * Protoveratrine hydrochloride
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 48 ug/kg
TOXIC EFFECTS :
   Peripheral Nerve and Sensation - flaccid paralysis without anesthesia
   (usually neuromuscular blockage)
   Behavioral - convulsions or effect on seizure threshold
   Lungs, Thorax, or Respiration - other changes
REFERENCE :
   JPETAB Journal of Pharmacology and Experimental Therapeutics.  (Williams &
   Wilkins Co., 428 E. Preston St., Baltimore, MD 21202)  V.1-    1909/10-
   Volume(issue)/page/year: 82,167,1944
 
                            *** END OF RECORD ***