*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : FK0279000
CHEMICAL NAME           : Cephalotaxine, 4-methyl-,
                          2-hydroxy-2-(3-methylbutyl)butanedioate (ester),
                          (3(R))-
CAS REGISTRY NUMBER     : 36804-95-2
LAST UPDATED            : 199209
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C28-H37-N-O8
MOLECULAR WEIGHT        : 515.66
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Deoxyharringtonine
   * 3(R)-Deoxyharringtonine
   * Desoxyharringtonin
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 16 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JOETD7 Journal of Ethnopharmacology.  (Elsevier Scientific Pub. Ireland
   Ltd., POB 85, Limerick, Ireland)  V.1-    1979-  Volume(issue)/page/year:
   24,1,1988
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 8800 ug/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JOETD7 Journal of Ethnopharmacology.  (Elsevier Scientific Pub. Ireland
   Ltd., POB 85, Limerick, Ireland)  V.1-    1979-  Volume(issue)/page/year:
   24,1,1988
 
                            *** END OF RECORD ***