*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : AK9800000
CHEMICAL NAME           : Acetohydroxamic acid, N-fluoren-2-yl-, nickel(2+)
                          complex
CAS REGISTRY NUMBER     : 14751-76-9
LAST UPDATED            : 199207
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C30-H24-N2-O4.Ni
MOLECULAR WEIGHT        : 535.27
WISWESSER LINE NOTATION : L B656 HHJ ENO&V1 &-NI- 2
COMPOUND DESCRIPTOR     : Tumorigen
SYNONYMS/TRADE NAMES :
   * N-Fluoren-2-ylacetohydroxamic acid, nickel(2+) complex
   * N-Hydroxy-2-acetylaminofluorene, nickelous chelate
   * Nickel complex with N-fluoren-2-ylacetohydroxamic acid
 
                       *** HEALTH HAZARD DATA ***
 
                          ** TUMORIGENIC DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 160 mg/kg/4W-I
TOXIC EFFECTS :
   Tumorigenic - neoplastic by RTECS criteria
   Skin and Appendages - tumors
   Tumorigenic - tumors at site of application
REFERENCE :
   CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut
   Sts., Philadelphia, PA 19106)  V.1-    1941-  Volume(issue)/page/year:
   25,527,1965

         *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***

NIOSH RECOMMENDED EXPOSURE LEVEL (REL) :
   NIOSH REL TO NICKEL, INORGANIC-air:10H CA TWA 0.015 mg(Ni)/m3
REFERENCE :
   NIOSH* National Institute for Occupational Safety and Health, U.S. Dept. of
   Health, Education, and Welfare, Reports and Memoranda.
   Volume(issue)/page/year: DHHS #92-100,1992

 
                            *** END OF RECORD ***