*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : AJ0600000
CHEMICAL NAME           : Acetic acid, nitrilotri-, trihydrazide
CAS REGISTRY NUMBER     : 80155-82-4
BEILSTEIN REFERENCE NO. : 1714871
REFERENCE               : 1-04-00-00483 (Beilstein Handbook Reference)
LAST UPDATED            : 199612
DATA ITEMS CITED        : 5
MOLECULAR FORMULA       : C6-H15-N7-O3
MOLECULAR WEIGHT        : 233.28
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Aminotriacetylhydrazine
   * AT-1902
   * N,N-Bis(2-hydrazino-2-oxoethyl)glycine hydrazide
   * Glycine, N,N-bis(2-hydrazino-2-oxoethyl)-, hydrazide
   * Nitrazine
   * Nitriloacetic acid trihydride
   * Nitrilotriacetic acid trihydrazide
   * Nitrilotriacetic hydrazide
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1343 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   KHTPBU Kexue Tongbao (Foreign Language Edition).  Science Bulletin.
   (Scientific and Technical Book Service, Ltd., POB 197, London, WC2N 4DE, UK)
    V.17, 1966; V.25-    1980- Suspended 1966-79. Volume(issue)/page/year:
   27,787,1982
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1736 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   KHTPBU Kexue Tongbao (Foreign Language Edition).  Science Bulletin.
   (Scientific and Technical Book Service, Ltd., POB 197, London, WC2N 4DE, UK)
    V.17, 1966; V.25-    1980- Suspended 1966-79. Volume(issue)/page/year:
   27,787,1982
 
                 ** OTHER MULTIPLE DOSE TOXICITY DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Mammal - dog
DOSE/DURATION           : 105 mg/kg/7D-I
TOXIC EFFECTS :
   Gastrointestinal - nausea or vomiting
   Gastrointestinal - other changes
   Related to Chronic Data - death
REFERENCE :
   KHTPBU Kexue Tongbao (Foreign Language Edition).  Science Bulletin.
   (Scientific and Technical Book Service, Ltd., POB 197, London, WC2N 4DE, UK)
    V.17, 1966; V.25-    1980- Suspended 1966-79. Volume(issue)/page/year:
   27,787,1982
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Mammal - dog
DOSE/DURATION           : 70 mg/kg/7D-I
TOXIC EFFECTS :
   Gastrointestinal - nausea or vomiting
   Gastrointestinal - other changes
   Related to Chronic Data - death
REFERENCE :
   KHTPBU Kexue Tongbao (Foreign Language Edition).  Science Bulletin.
   (Scientific and Technical Book Service, Ltd., POB 197, London, WC2N 4DE, UK)
    V.17, 1966; V.25-    1980- Suspended 1966-79. Volume(issue)/page/year:
   27,787,1982
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 87500 ug/kg/7D-I
TOXIC EFFECTS :
   Gastrointestinal - other changes
   Related to Chronic Data - death
REFERENCE :
   KHTPBU Kexue Tongbao (Foreign Language Edition).  Science Bulletin.
   (Scientific and Technical Book Service, Ltd., POB 197, London, WC2N 4DE, UK)
    V.17, 1966; V.25-    1980- Suspended 1966-79. Volume(issue)/page/year:
   27,787,1982
 
                            *** END OF RECORD ***