*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : AI9155000
CHEMICAL NAME           : Acetic acid, methylnitrosaminomethyl-d3 ester
CAS REGISTRY NUMBER     : 67557-57-7
BEILSTEIN REFERENCE NO. : 5255090
LAST UPDATED            : 199612
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C4-H5-D3-N2-O3
MOLECULAR WEIGHT        : 135.14
WISWESSER LINE NOTATION : ONN1&1OV1 &4/H-2 3
COMPOUND DESCRIPTOR     : Tumorigen
SYNONYMS/TRADE NAMES :
   * Acetoxymethyltrideuteromethylnitrosamine
   * Methylamine, 1-acetoxy-N-nitroso-N-trideuteromethyl-
   * Nitroso-N-(1-acetoxymethyl)trideuteromethylamine
   * Trideuteromethyl acetoxymethylnitrosamine
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 120 mg/kg
TOXIC EFFECTS :
   Lungs, Thorax, or Respiration - acute pulmonary edema
   Gastrointestinal - ulceration or bleeding from stomach
   Liver - other changes
REFERENCE :
   ZKKOBW Zeitschrift fuer Krebsforschung und Klinische Onkologie.  (Berlin,
   Fed. Rep. Ger.)  V.76-92, 1971-78.  For publisher information, see JCROD7.
   Volume(issue)/page/year: 91,317,1978
 
                          ** TUMORIGENIC DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 51 mg/kg/90D-I
TOXIC EFFECTS :
   Tumorigenic - equivocal tumorigenic agent by RTECS criteria
   Gastrointestinal - tumors
REFERENCE :
   ZKKOBW Zeitschrift fuer Krebsforschung und Klinische Onkologie.  (Berlin,
   Fed. Rep. Ger.)  V.76-92, 1971-78.  For publisher information, see JCROD7.
   Volume(issue)/page/year: 91,317,1978
 
                            *** END OF RECORD ***