*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : AH5250000
CHEMICAL NAME           : Acetic acid, (ethylenedinitrilo)tetra-, trisodium
                          salt
CAS REGISTRY NUMBER     : 150-38-9
LAST UPDATED            : 199710
DATA ITEMS CITED        : 10
MOLECULAR FORMULA       : C10-H13-N2-O8.3Na
MOLECULAR WEIGHT        : 358.22
WISWESSER LINE NOTATION : QV1N1VO2N1VO1VO &-NA- 3
COMPOUND DESCRIPTOR     : Tumorigen
                          Mutagen
SYNONYMS/TRADE NAMES :
   * Edetate trisodium
   * EDTA trisodium salt (trihydrate)
   * Ethylenediamineacetic acid trisodium salt
   * Ethylenediaminetetraacetic acid, trisodium salt
   * Glycine, N,N'-1,2-ethanediylbis(N-(carboxymethyl)-, trisodium salt
   * NCI-C03974
   * Nevanaid-B powder
   * Perma kleer 50, trisodium salt
   * Sequestrene Na3
   * Sequestrene trisodium
   * Sequestrene trisodium salt
   * Trilon AO
   * Trinatrium ethylendiamintetraacetat
   * Trisodium edetate
   * Trisodium EDTA
   * Trisodium ethylenediaminetetraacetate
   * Trisodium hydrogen ethylenediaminetetraacetate
   * Trisodium hydrogen (ethylenedinitrilo)tetraacetate
   * Trisodium versenate
   * Versene 9
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 2150 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   NCILB* Progress Report for Contract No. NIH-NCI-E-C-72-3252, Submitted to
   the National Cancer Institute by Litton Bionetics, Inc.  (Bethesda, MD)
   Volume(issue)/page/year: NCI-E-C-72-3252,1973
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 2150 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   NCILB* Progress Report for Contract No. NIH-NCI-E-C-72-3252, Submitted to
   the National Cancer Institute by Litton Bionetics, Inc.  (Bethesda, MD)
   Volume(issue)/page/year: NCI-E-C-72-3252,1973
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 300 mg/kg
TOXIC EFFECTS :
   Kidney, Ureter, Bladder - changes in tubules (including acute renal failure,
   acute tubular necrosis)
REFERENCE :
   REPMBN Revue d'Epidemiologie, Medecine Sociale et Sante Publique.  (Masson
   Editeur, 120 Blvd. Saint-Germain, F-75280 Paris Cedex O6, France)  V.1-
   1953-  Volume(issue)/page/year: 10,391,1962

                    *** U.S. STANDARDS AND REGULATIONS ***
 
   EPA FIFRA 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATION
   FEREAC Federal Register.  (U.S. Government Printing Office, Supt. of
   Documents, Washington, DC 20402) V.1-    1936-  Volume(issue)/page/year:
   54,7740,1989

         *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***

NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :
   NOHS - National Occupational Hazard Survey (1974)
     NOHS Hazard Code - 82120
       No. of Facilities: 2356 (estimated)
       No. of Industries: 19
       No. of Occupations: 24
       No. of Employees: 26820 (estimated)
   
   NOES - National Occupational Exposure Survey (1983)
     NOES Hazard Code - 82120
       No. of Facilities: 5994 (estimated)
       No. of Industries: 32
       No. of Occupations: 34
       No. of Employees: 50542 (estimated)
       No. of Female Employees: 14938 (estimated)

                          *** STATUS IN U.S. ***
 
   EPA GENETOX PROGRAM 1988, Negative: Carcinogenicity-mouse/rat
   
   EPA TSCA Section 8(b) CHEMICAL INVENTORY
   
   EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JUNE 1998
   
   NCI Carcinogenesis Bioassay (feed);no evidence:mouse,rat
   NCITR* National Cancer Institute Carcinogenesis Technical Report Series.
   (Bethesda, MD)  No.0-205. For publisher information, see NTPTR*.
   Volume(issue)/page/year: NCI-TR-11,77

 
                            *** END OF RECORD ***