*** CHEMICAL IDENTIFICATION ***
RTECS NUMBER : FD7700000
CHEMICAL NAME : Carbanilic acid, m-chloro-, 4-chloro-2-butynyl ester
CAS REGISTRY NUMBER : 101-27-9
BEILSTEIN REFERENCE NO. : 2376181
REFERENCE : 4-12-00-01149 (Beilstein Handbook Reference)
LAST UPDATED : 199706
DATA ITEMS CITED : 13
MOLECULAR FORMULA : C11-H9-Cl2-N-O2
MOLECULAR WEIGHT : 258.11
WISWESSER LINE NOTATION : G2UU2OVMR CG
COMPOUND DESCRIPTOR : Agricultural Chemical
Mutagen
SYNONYMS/TRADE NAMES :
* A-980
* Barban
* Barbane
* 2-Butyn-1-ol, 4-chloro-, m-chlorocarbanilate
* 2-Butynyl-4-chloro-m-chlorocarbanilate
* C-847
* Carbamic acid, (3-chlorophenyl)-, 4-chloro-2-butynyl ester
* Carbyne
* CBN
* (4-Chloor-but-2-yn-yl)-N-(3-chloor-fenyl)-carbamaat
* (4-Chlor-but-2-in-yl)-N-(3-chlor-phenyl)-carbamat
* 4-Chlorobut-2-ynyl-m-chlorocarbanilate
* 4-Chloro-2-butynyl-m-chlorocarbanilate
* 4-Chlorobut-2-ynyl 3-chlorophenylcarbamate
* 4-Chloro-2-butynyl N-(3-chlorophenyl)carbamate
* m-Chlorocarbanilic acid, 4-chloro-2-butynyl ester
* N-(3-Chloro phenyl) carbamate de 4-chloro 2-butynyle
* (3-Chlorophenyl)carbamic acid 4-chloro-2-butynyl ester
* (4-Cloro-but-2-in-il)-N-(3-cloro-fenil)-carbammato
* Fisons B25
* Neoban
* S-847
*** HEALTH HAZARD DATA ***
** ACUTE TOXICITY DATA **
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 527 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
85GMAT "Toxicometric Parameters of Industrial Toxic Chemicals Under Single
Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects,
GKNT, 1982 Volume(issue)/page/year: -,35,1982
TYPE OF TEST : LC50 - Lethal concentration, 50 percent kill
ROUTE OF EXPOSURE : Inhalation
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 27400 mg/m3/4H
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J.,
Prague, Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year: -,952,1986
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Administration onto the skin
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : >1600 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
WRPCA2 World Review of Pest Control. (London, UK) V.1-10, 1962-71.
Discontinued. Volume(issue)/page/year: 9,119,1970
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Unreported
SPECIES OBSERVED : Rodent - rat
DOSE/DURATION : 527 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
EQSSDX Environmental Quality and Safety, Supplement. (Stuttgart, Fed. Rep.
Ger.) V.1-5, 1975-76. Discontinued. Volume(issue)/page/year: 3,618,1975
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 322 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
FATOAO Farmakologiya i Toksikologiya (Moscow). For English translation, see
PHTXA6 and RPTOAN. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.2-
1939- Volume(issue)/page/year: 35,356,1972
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - rabbit
DOSE/DURATION : 600 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
PAREAQ Pharmacological Reviews. (Williams & Wilkins, 428 E. Preston St.,
Baltimore, MD 21202) V.1- 1949- Volume(issue)/page/year: 14,225,1962
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Administration onto the skin
SPECIES OBSERVED : Rodent - rabbit
DOSE/DURATION : 23000 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
85DPAN "Wirksubstanzen der Pflanzenschutz und Schadlingsbekampfungsmittel,"
Perkow, W., Berlin, Verlag Paul Parey, 1971-1976 Volume(issue)/page/year:
-,-,1971/1976
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - guinea pig
DOSE/DURATION : 240 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
PAREAQ Pharmacological Reviews. (Williams & Wilkins, 428 E. Preston St.,
Baltimore, MD 21202) V.1- 1949- Volume(issue)/page/year: 14,225,1962
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Unreported
SPECIES OBSERVED : Mammal - species unspecified
DOSE/DURATION : 240 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
30ZDA9 "Chemistry of Pesticides," Melnikov, N.N., New York, Springer-Verlag
New York, Inc., 1971 Volume(issue)/page/year: -,202,1971
** MUTATION DATA **
TYPE OF TEST : DNA repair
TEST SYSTEM : Bacteria - Bacillus subtilis
DOSE/DURATION : 20 ug/disc
REFERENCE :
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE
Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 40,19,1976
*** REVIEWS ***
TOXICOLOGY REVIEW
DTTIAF Deutsche Tieraerztliche Wochenschrift. (Hanover, Fed. Rep. Ger.)
V.1-77, 1893-1970. Volume(issue)/page/year: 80,485,1973
*** U.S. STANDARDS AND REGULATIONS ***
EPA FIFRA 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATION
FEREAC Federal Register. (U.S. Government Printing Office, Supt. of
Documents, Washington, DC 20402) V.1- 1936- Volume(issue)/page/year:
54,7740,1989
*** STATUS IN U.S. ***
EPA GENETOX PROGRAM 1988, Positive: B subtilis rec assay
*** END OF RECORD ***