*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : FA2100000
CHEMICAL NAME           : Carbamic acid, dimethyl-,
                          1-isopropyl-3-methylpyrazol-5-yl ester
CAS REGISTRY NUMBER     : 119-38-0
BEILSTEIN REFERENCE NO. : 0201858
REFERENCE               : 5-23-10-00529 (Beilstein Handbook Reference)
LAST UPDATED            : 199612
DATA ITEMS CITED        : 10
MOLECULAR FORMULA       : C10-H17-N3-O2
MOLECULAR WEIGHT        : 211.30
WISWESSER LINE NOTATION : T5NNJ AY1&1 C1 EOVN1&1
COMPOUND DESCRIPTOR     : Agricultural Chemical
                          Tumorigen
                          Mutagen
SYNONYMS/TRADE NAMES :
   * Dimethylcarbamic acid 3-methyl-1-(1-methylethyl)-1H-pyrazol-5-yl ester
   * Dimethylcarbamate de L-isopropyl 3-methyl 5-pyrazolyle
   * Dimethyl-5-(l-isopropyl-3-methyl-pyrazolyl)-carbamate
   * ENT 19,060
   * G 23611
   * Geigy G-23611
   * Isolan
   * Isolane
   * (1-Isopropil-3-metil-1H-pirazol-5-il)-N,N-dimetil-carbammato
   * (1-Isopropyl-3-methyl-1H-pyrazol-5-yl)-N,N-dimethylcarbamaat
   * (1-Isopropyl-3-methyl-1H-pyrazol-5-yl)-N,N-dimethyl-carbamat
   * Isopropylmethylpyrazolyl dimethylcarbamate
   * 1-Isopropyl-3-methyl-5-pyrazolyl dimethylcarbamate
   * 1-Isopropyl-3-methylpyrazolyl-(5)-dimethylcarbamate
   * 1-Isopropyl-3-methyl-5-pyrazolylester kyseliny dimethylkarbaminove
   * 5-Methyl-2-isopropyl-3-pyrazolyl dimethylcarbamate
   * OMS 62
   * Primin
   * Pyrazol-5-ol, 1-isopropyl-3-methyl-, dimethylcarbamate
   * Saolan
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 10800 ug/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   PESTD5 Proceedings of the European Society of Toxicology.  (Amsterdam,
   Netherlands)  V.16-18, 1975-77.  Discontinued.  Volume(issue)/page/year:
   17,351,1976
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 5600 ug/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   85DPAN "Wirksubstanzen der Pflanzenschutz und Schadlingsbekampfungsmittel,"
   Perkow, W., Berlin, Verlag Paul Parey, 1971-1976  Volume(issue)/page/year:
   -,-,1971/1976
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 2150 ug/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   PESTD5 Proceedings of the European Society of Toxicology.  (Amsterdam,
   Netherlands)  V.16-18, 1975-77.  Discontinued.  Volume(issue)/page/year:
   17,351,1976
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 9800 ug/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   PESTD5 Proceedings of the European Society of Toxicology.  (Amsterdam,
   Netherlands)  V.16-18, 1975-77.  Discontinued.  Volume(issue)/page/year:
   17,351,1976
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   TXAPA9 Toxicology and Applied Pharmacology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1959-  Volume(issue)/page/year:
   6,402,1964
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Unreported
SPECIES OBSERVED        : Mammal - species unspecified
DOSE/DURATION           : 11 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   30ZDA9 "Chemistry of Pesticides," Melnikov, N.N., New York, Springer-Verlag
   New York, Inc., 1971  Volume(issue)/page/year: -,197,1971
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Bird - wild bird species
DOSE/DURATION           : 8600 ug/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   TXAPA9 Toxicology and Applied Pharmacology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1959-  Volume(issue)/page/year:
   21,315,1972
 
                          ** TUMORIGENIC DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 6600 mg/kg/78W-I
TOXIC EFFECTS :
   Tumorigenic - equivocal tumorigenic agent by RTECS criteria
   Lungs, Thorax, or Respiration - tumors
   Liver - tumors
REFERENCE :
   NTIS** National Technical Information Service.  (Springfield, VA 22161)
   Formerly U.S. Clearinghouse for Scientific & Technical Information.
   Volume(issue)/page/year: PB223-159
 
                            ** MUTATION DATA **
 
TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Yeast - Saccharomyces cerevisiae
DOSE/DURATION           : 5 ppm
REFERENCE :
   RSTUDV Rivista di Scienza e Technologia degli Alimenti e di Nutrizione
   Umana.  Review of Science and Technology of Food and Human Nutrition.
   (Bologna, Italy)  V.5-6, 1975-76.  Discontinued.  Volume(issue)/page/year:
   6,161,1976

                              *** REVIEWS ***
 
   TOXICOLOGY REVIEW
   DTTIAF Deutsche Tieraerztliche Wochenschrift.  (Hanover, Fed. Rep. Ger.)
   V.1-77, 1893-1970.  Volume(issue)/page/year: 80,485,1973

 
                            *** END OF RECORD ***