*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : EY8557000
CHEMICAL NAME           : Carbamic acid,
                          (2-amino-6-(((4-fluorophenyl)methyl)amino)-3-pyridiny
                          l)-, 2-propenyl ester, monohydrochloride
CAS REGISTRY NUMBER     : 149690-78-8
LAST UPDATED            : 199509
DATA ITEMS CITED        : 3
MOLECULAR FORMULA       : C16-H17-F-N4-O2.Cl-H
MOLECULAR WEIGHT        : 352.83
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   *   2-Amino-3-((prop-1-en-3-yl)oxycarbonylamino)-6-(4-fluorobenzylamino)pyri
     dine hydrochloride
   * D-19050
   * Prop-1-en-3-yl (N-(2-amino-6-(4-fluorobenzyl)amino)pyridin-3-yl)carbamate 
    hydrochloride
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 1030 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 43,627,1993
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 675 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 43,627,1993
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 75 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 43,627,1993
 
                            *** END OF RECORD ***