*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : ET5980000
CHEMICAL NAME           : Butyric acid, 2-phenyl-,
                          2-(3-methyl-2-phenylmorpholino)ethyl ester,
                          hydrochloride
CAS REGISTRY NUMBER     : 6474-85-7
LAST UPDATED            : 197905
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C23-H29-N-O3.Cl-H
MOLECULAR WEIGHT        : 403.99
WISWESSER LINE NOTATION : T6N DOTJ A2OVY2&R BR& C1 &GH
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * alpha-Ethylbenzeneacetic acid 2-(3-methyl-2-phenyl-4-morpholinyl)ethyl  
   ester hydrochloride
   * Fenbutrazate hydrochloride
   * 2-(3-Methyl-2-phenylmorpholino)ethyl 2-phenylbutyrate hydrochloride
   * 4-Morpholineethanol, 3-methyl-2-phenyl-, 2-phenylbutyrate (ester)  
   hydrochloride
   * Phenbutrazate hydrochloride
   *   Phenyl-aethyl-essigsaeure-(phenyl-methyl)-morpholino-N-aethanolester-hyd
     rochlorid
   * 2-Phenylbutyric acid 2-(3-methyl-2-phenylmorpholino)ethyl ester  
   hydrochloride
   * R 381
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 3200 mg/kg
TOXIC EFFECTS :
   Behavioral - tremor
   Behavioral - excitement
   Behavioral - changes in motor activity (specific assay)
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 5,526,1955
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 2800 mg/kg
TOXIC EFFECTS :
   Behavioral - tremor
   Behavioral - excitement
   Behavioral - changes in motor activity (specific assay)
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 5,526,1955
 
                            *** END OF RECORD ***