*** CHEMICAL IDENTIFICATION ***
RTECS NUMBER : EU9850000
CHEMICAL NAME : Cadmium, bis(diethyldithiocarbamato)-
CAS REGISTRY NUMBER : 14239-68-0
LAST UPDATED : 199712
DATA ITEMS CITED : 32
MOLECULAR FORMULA : C10-H20-Cd-N2-S4
MOLECULAR WEIGHT : 408.96
WISWESSER LINE NOTATION : 2N2&YUS&S 2-CD-
COMPOUND DESCRIPTOR : Tumorigen
Mutagen
SYNONYMS/TRADE NAMES :
* Bis(diethyldithiocarbamato)cadmium
* Cadmate
* Cadmium di(diethyldithiocarbamate)
* Cadmium diethyl dithiocarbamate
* Carbamic acid, diethyldithio-, cadmium salt
* Cd diethyldithiocarbamate
*** HEALTH HAZARD DATA ***
** ACUTE TOXICITY DATA **
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intraperitoneal
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 650 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
ACLSCP Annals of Clinical and Laboratory Science. (1833 Delancey Pl.,
Philadelphia, PA 19103) V.1- 1971- Volume(issue)/page/year: 11,476,1981
** TUMORIGENIC DATA **
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 7100 mg/kg/78W-I
TOXIC EFFECTS :
Tumorigenic - equivocal tumorigenic agent by RTECS criteria
Lungs, Thorax, or Respiration - tumors
Liver - tumors
REFERENCE :
NTIS** National Technical Information Service. (Springfield, VA 22161)
Formerly U.S. Clearinghouse for Scientific & Technical Information.
Volume(issue)/page/year: PB223-159
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Subcutaneous
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 1000 mg/kg
TOXIC EFFECTS :
Tumorigenic - equivocal tumorigenic agent by RTECS criteria
Lungs, Thorax, or Respiration - tumors
Blood - tumors
REFERENCE :
NTIS** National Technical Information Service. (Springfield, VA 22161)
Formerly U.S. Clearinghouse for Scientific & Technical Information.
Volume(issue)/page/year: PB223-159
** MUTATION DATA **
TYPE OF TEST : Mutation in microorganisms
TEST SYSTEM : Bacteria - Salmonella typhimurium
DOSE/DURATION : 10 ug/plate
REFERENCE :
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE
Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 68,313,1979
TYPE OF TEST : DNA damage
TEST SYSTEM : Bacteria - Escherichia coli
DOSE/DURATION : 1 umol/L
REFERENCE :
ARTODN Archives of Toxicology. (Springer-Verlag, Heidelberger Pl. 3, D-1000
Berlin 33, Fed. Rep. Ger.) V.32- 1974- Volume(issue)/page/year:
46,277,1980
*** REVIEWS ***
ACGIH TLV-TWA 0.01 mg(Cd)/m3, inhalable dust
DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices
(BEIs) booklet issues by American Conference of Governmental Industrial
Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year:
TLV/BEI,1997
ACGIH TLV-TWA 0.002 mg(Cd)/m3, respirable dust
DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices
(BEIs) booklet issues by American Conference of Governmental Industrial
Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year:
TLV/BEI,1997
ACGIH TLV-Suspected human carcinogen
DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices
(BEIs) booklet issues by American Conference of Governmental Industrial
Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year:
TLV/BEI,1997
IARC Cancer Review:Human Sufficient Evidence
IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals
to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210)
V.1- 1972- Volume(issue)/page/year: 58,119,1993
IARC Cancer Review:Animal Sufficient Evidence
IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals
to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210)
V.1- 1972- Volume(issue)/page/year: 58,119,1993
IARC Cancer Review:Group 1
IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals
to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210)
V.1- 1972- Volume(issue)/page/year: 58,119,1993
*** U.S. STANDARDS AND REGULATIONS ***
MSHA STANDARD-air:TWA 0.2 mg(Cd)/m3
DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices
(BEIs) booklet issues by American Conference of Governmental Industrial
Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: 3,34,1971
*** OCCUPATIONAL EXPOSURE LIMITS ***
OEL-ARAB Republic of Egypt:TWA 0.05 mg(Cd)/m3 JAN 1993
OEL-AUSTRALIA:TWA 0.05 mg(Cd)/m3 JAN 1993
OEL-BELGIUM:TWA 0.05 mg(Cd)/m3 JAN 1993
OEL-DENMARK:TWA 0.01 mg(Cd)/m3 JAN 1993
OEL-FINLAND:TWA 0.02 mg(Cd)/m3;Carcinogen JAN 1993
OEL-GERMANY;Carcinogen JAN 1993
OEL-INDIA:TWA 0.05 mg(Cd)/m3 JAN 1993
OEL-JAPAN:TWA 0.05 mg(Cd)/m3 JAN 1993
OEL-THE NETHERLANDS:TWA 0.02 mg(Cd)/m3;STEL 0.1 mg(Cd)/m3 JAN 1993
OEL-THE PHILIPPINES:TWA 0.2 mg(Cd)/m3 JAN 1993
OEL-RUSSIA:TWA 0.01 mg(Cd)/m3;STEL 0.05 mg(Cd)/m3 JAN 1993
OEL-SWEDEN:TWA 0.02 mg(Cd)/m3;Carcinogen JAN 1993
OEL-SWITZERLAND:TWA 0.05 mg(Cd)/m3 JAN 1993
OEL-THAILAND:TWA 0.2 mg(Cd)/m3;STEL 0.5 mg(Cd)/m3 JAN 1993
OEL-TURKEY:TWA 0.2 mg(Cd)/m3 JAN 1993
OEL-UNITED KINGDOM:TWA 0.01 mg(Cd)/m3 JAN 1993
OEL IN BULGARIA, COLOMBIA, JORDAN, KOREA check ACGIH TLV
OEL IN NEW ZEALAND, SINGAPORE, VIETNAM check ACGIH TLV
*** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***
NIOSH RECOMMENDED EXPOSURE LEVEL (REL) :
NIOSH REL TO CADMIUM, dust and fume-air:CA lowest feasible conc.
REFERENCE :
NIOSH* National Institute for Occupational Safety and Health, U.S. Dept. of
Health, Education, and Welfare, Reports and Memoranda.
Volume(issue)/page/year: DHHS #92-100,1992
*** STATUS IN U.S. ***
EPA TSCA Section 8(b) CHEMICAL INVENTORY
*** END OF RECORD ***