*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : EU4131000
CHEMICAL NAME           : Butyrophenone,
                          4'-fluoro-4-(methyl(1,2,3,4-tetrahydro-9H-pyrido(3,4-
                          b)indol-2-ylmethyl) amino)-
CAS REGISTRY NUMBER     : 101221-63-0
LAST UPDATED            : 198609
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C23-H26-F-N3-O
MOLECULAR WEIGHT        : 379.52
WISWESSER LINE NOTATION : T B656 EM HMT&&J D1N1&3VR DF
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   *   4'-Fluoro-4-(methyl(1,2,3,4-tetrahydro-9H-pyrido(3,4-b)indol-2-ylmethyl)
     amino)butyrophenone
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 600 mg/kg
TOXIC EFFECTS :
   Behavioral - altered sleep time (including change in righting reflex)
   Behavioral - changes in motor activity (specific assay)
   Behavioral - ataxia
REFERENCE :
   EJMCA5 European Journal of Medicinal Chemistry--Chimie Therapeutique.
   (Editions Scientifiques Elsevier, 29 rue Buffon, F-75005, Paris, France)
   V.9-    1974-  Volume(issue)/page/year: 17,312,1982
 
                            *** END OF RECORD ***