*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : EU4020000
CHEMICAL NAME           : Butyrophenone,
                          4'-fluoro-4-(2-methyl-1,2,3,4,5,6,7,8-octahydro-13H-1
                          ,4,-diazecino(8,7-b) indol-5-yl)-
CAS REGISTRY NUMBER     : 101247-79-4
LAST UPDATED            : 198609
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C25-H30-F-N3-O
MOLECULAR WEIGHT        : 407.58
WISWESSER LINE NOTATION : T B65-10- HM KN NN&&TJ K1 N3VR DF
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   *   2-Methyl-5-(gamma-(p-fluorobenzoyl)propyl)-1,2,3,4,5,6,7,8-octahydro-2,5
     -indolodiazocine
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 500 mg/kg
TOXIC EFFECTS :
   Behavioral - altered sleep time (including change in righting reflex)
   Behavioral - changes in motor activity (specific assay)
   Behavioral - ataxia
REFERENCE :
   EJMCA5 European Journal of Medicinal Chemistry--Chimie Therapeutique.
   (Editions Scientifiques Elsevier, 29 rue Buffon, F-75005, Paris, France)
   V.9-    1974-  Volume(issue)/page/year: 17,312,1982
 
                            *** END OF RECORD ***