*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : EU4005100
CHEMICAL NAME           : Butyrophenone,
                          4'-fluoro-4-(9-methyl-3-azaspiro(5.5)undec-3-yl)-
CAS REGISTRY NUMBER     : 64-59-5
BEILSTEIN REFERENCE NO. : 1348999
REFERENCE               : 5-20-04-00449 (Beilstein Handbook Reference)
LAST UPDATED            : 199612
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C21-H30-F-N-O
MOLECULAR WEIGHT        : 331.52
WISWESSER LINE NOTATION : T6N DXTJ A3VR DF& D-& AL6XTJ D1
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 4'-Fluoro-4-(9-methyl-3-azaspiro(5.5)undec-3-yl)butyrophenone
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 75 mg/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
   Behavioral - ataxia
   Biochemical - Metabolism (Intermediary) - effect on inflammation or
   mediation of inflammation
REFERENCE :
   JMCMAR Journal of Medicinal Chemistry.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
   20037)  V.6-    1963-  Volume(issue)/page/year: 8,62,1965
 
                            *** END OF RECORD ***