*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : EU3556500
CHEMICAL NAME           : Butyrophenone,
                          4'-fluoro-4-(3-(3-indolylmethyl)-4-methyl-1-piperazin
                          yl)-
CAS REGISTRY NUMBER     : 83892-87-9
OTHER CAS REGISTRY NOS. : 101221-61-8
BEILSTEIN REFERENCE NO. : 5635213
LAST UPDATED            : 199612
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C24-H28-F-N3-O
MOLECULAR WEIGHT        : 393.55
WISWESSER LINE NOTATION : T56 BMJ D1- BT6N DNTJ A1 D3VR DF
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 1-Butanone,  
   1-(4-fluorophenyl)-4-(3-(1H-indol-3-ylmethyl)-4-methyl-1-piperazinyl)-
   * 4'-Fluoro-4-(3-(3-indolylmethyl)-4-methyl-1-piperazinyl)butyrophenone
   * 1-Methyl-2-(3-indolylmethyl)-4-gamma-(p-fluorobenzoyl)propylpiperazine
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 800 mg/kg
TOXIC EFFECTS :
   Behavioral - altered sleep time (including change in righting reflex)
   Behavioral - changes in motor activity (specific assay)
   Behavioral - ataxia
REFERENCE :
   EJMCA5 European Journal of Medicinal Chemistry--Chimie Therapeutique.
   (Editions Scientifiques Elsevier, 29 rue Buffon, F-75005, Paris, France)
   V.9-    1974-  Volume(issue)/page/year: 17,312,1982
 
                            *** END OF RECORD ***