*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : EU1576000
CHEMICAL NAME           : Butyrophenone,
                          4-(4-(p-chlorophenyl)-4-hydroxypiperidino)-4'-fluoro-
                          2-hydroxy-
CAS REGISTRY NUMBER     : 51037-48-0
BEILSTEIN REFERENCE NO. : 1510378
LAST UPDATED            : 199612
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C21-H23-Cl-F-N-O3
MOLECULAR WEIGHT        : 391.90
WISWESSER LINE NOTATION : T6NTJ A2YQR DF& DQ DR DG
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   *   4-(4-(p-Chlorophenyl)-4-hydroxypiperidino)-4'-fluoro-2-hydroxybutyrophen
     one
   *   1-(4-Fluorophenyl)-2-hydroxy-4-(4-hydroxy-4-(4-chlorophenyl)-1-piperidyl
     )-1-butanone
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 55 mg/kg
TOXIC EFFECTS :
   Behavioral - changes in motor activity (specific assay)
   Behavioral - rigidity (including catalepsy)
REFERENCE :
   FRPSAX Farmaco, Edizione Scientifica. (Casella Postale 227, 27100 Pavia,
   Italy)  V.8-43 1953-88 For publisher information, see FRMCE8
   Volume(issue)/page/year: 35,605,1980
 
                            *** END OF RECORD ***