*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : EU1138510
CHEMICAL NAME           : Butyrophenone, 4-(2-azaspiro(4.5)dec-2-yl)-4'-fluoro-
CAS REGISTRY NUMBER     : 1093-22-7
BEILSTEIN REFERENCE NO. : 1430820
REFERENCE               : 5-20-04-00402 (Beilstein Handbook Reference)
LAST UPDATED            : 199612
DATA ITEMS CITED        : 1
MOLECULAR FORMULA       : C19-H26-F-N-O
MOLECULAR WEIGHT        : 303.46
WISWESSER LINE NOTATION : T5N CXTJ A3VR DF& C-& AL6XTJ
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 4-(2-Azaspiro(4.5)dec-2-yl)-4'-fluoro-butyrophenone
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 50 mg/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
   Behavioral - changes in motor activity (specific assay)
   Behavioral - ataxia
REFERENCE :
   JMCMAR Journal of Medicinal Chemistry.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
   20037)  V.6-    1963-  Volume(issue)/page/year: 8,62,1965
 
                            *** END OF RECORD ***