*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : ET4250000
CHEMICAL NAME           : Butyric acid,
                          4-(((3-hydroxy-5-(hydroxymethyl)-2-methyl-4-pyridyl)m
                          ethyl)amino)-, hydrochloride
CAS REGISTRY NUMBER     : 73758-58-4
LAST UPDATED            : 197906
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C12-H18-N2-O4.Cl-H
MOLECULAR WEIGHT        : 290.78
WISWESSER LINE NOTATION : T6NJ B1 CQ D1M3VQ E1Q &GH
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * 4-(3-Hydroxy-5-hydroxymethyl-2-methyl-4-pyridyl)methylaminobutyric acid,  
   hydrochloride
   * Pyridoxyl-gamma-aminobuttersaeure hydrochlorid
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 7100 mg/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
   Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 11,922,1961
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 2150 mg/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
   Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 11,922,1961
 
                            *** END OF RECORD ***