*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : ES9900000
CHEMICAL NAME           : Butyric acid, 2-(dimethylaminomethyl)-2-phenyl-,
                          benzyl ester, hydrochloride
CAS REGISTRY NUMBER     : 510-83-8
LAST UPDATED            : 199709
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C20-H25-N-O2.Cl-H
MOLECULAR WEIGHT        : 347.92
WISWESSER LINE NOTATION : 1N1&1X2&R&VO1R &GH
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * Benzeneacetic acid, alpha-((dimethylamino)methyl)-alpha-ethyl-,  
   phenylmethyl ester, HCl
   * Benzyl-beta-dimethyl-amino-alpha-phenyl-alpha-ethyl-propionate  
   hydrochloride
   * DL 219
   * Hydratropic acid, beta-(dimethylamino)-alpha-ethyl-, benzyl ester,  
   hydrochloride
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 475 mg/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
   Behavioral - convulsions or effect on seizure threshold
   Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
   JPETAB Journal of Pharmacology and Experimental Therapeutics.  (Williams &
   Wilkins Co., 428 E. Preston St., Baltimore, MD 21202)  V.1-    1909/10-
   Volume(issue)/page/year: 70,179,1940
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 47 mg/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
   Behavioral - convulsions or effect on seizure threshold
   Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
   JPETAB Journal of Pharmacology and Experimental Therapeutics.  (Williams &
   Wilkins Co., 428 E. Preston St., Baltimore, MD 21202)  V.1-    1909/10-
   Volume(issue)/page/year: 70,179,1940
 
                            *** END OF RECORD ***