*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : ES7175000
CHEMICAL NAME           : Butyric acid, 4-amino-3-phenyl-
CAS REGISTRY NUMBER     : 1078-21-3
BEILSTEIN REFERENCE NO. : 2804903
REFERENCE               : 4-14-00-01723 (Beilstein Handbook Reference)
LAST UPDATED            : 199701
DATA ITEMS CITED        : 4
MOLECULAR FORMULA       : C10-H13-N-O2
MOLECULAR WEIGHT        : 179.24
WISWESSER LINE NOTATION : Z1YR&1VQ
COMPOUND DESCRIPTOR     : Drug
                          Human
SYNONYMS/TRADE NAMES :
   * beta-(Aminomethyl)benzenepropanoic acid
   * beta-(Aminomethyl)hydrocinnamic acid
   * 4-Amino-3-phenylbutanoic acid
   * 4-Amino-3-phenylbutyric acid
   * Fenibut
   * Fenigam
   * Fenigama
   * Pgaba
   * Phenibut
   * Phenigam
   * Phenigama
   * beta-Phenyl-gamma-aminobutyrate
   * beta-Phenyl-gamma-aminobutyric acid
   * Phenylgam
   * Phenylgamma
   * PhGaba
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Human
DOSE/DURATION           : 5 mg/kg
TOXIC EFFECTS :
   Behavioral - sleep
   Behavioral - somnolence (general depressed activity)
   Behavioral - hallucinations, distorted perceptions
REFERENCE :
   BEXBAN Bulletin of Experimental Biology and Medicine (English Translation).
   Translation of BEBMAE. (Plenum Pub. Corp., 233 Spring St., New York, NY
   10013)  V.41-    1956-  Volume(issue)/page/year: 57,52,1964
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 700 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   BEXBAN Bulletin of Experimental Biology and Medicine (English Translation).
   Translation of BEBMAE. (Plenum Pub. Corp., 233 Spring St., New York, NY
   10013)  V.41-    1956-  Volume(issue)/page/year: 57,52,1964
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 900 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   BEXBAN Bulletin of Experimental Biology and Medicine (English Translation).
   Translation of BEBMAE. (Plenum Pub. Corp., 233 Spring St., New York, NY
   10013)  V.41-    1956-  Volume(issue)/page/year: 57,52,1964

                          *** STATUS IN U.S. ***
 
   EPA TSCA Section 8(b) CHEMICAL INVENTORY

 
                            *** END OF RECORD ***