*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : ES6650000
CHEMICAL NAME           : Butyric acid, 4-amino-, ethyl ester, hydrochloride
CAS REGISTRY NUMBER     : 6937-16-2
LAST UPDATED            : 198503
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C6-H13-N-O2.Cl-H
MOLECULAR WEIGHT        : 167.66
WISWESSER LINE NOTATION : Z3VO2 &GH
COMPOUND DESCRIPTOR     : Drug
SYNONYMS/TRADE NAMES :
   * gamma-Aminobutyric acid ethyl ester hydrochloride
   * DF 503
   * Eegaba
   * Ethyl-gamma-aminobutyrate, hydrochloride
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1350 mg/kg
TOXIC EFFECTS :
   Behavioral - tremor
   Behavioral - convulsions or effect on seizure threshold
   Lungs, Thorax, or Respiration - respiratory stimulation
REFERENCE :
   DPHFAK Dissertationes Pharmaceuticae et Pharmacologicae.  (Warsaw, Poland)
   V.18-24, 1966-72.  For publisher information, see PJPPAA.
   Volume(issue)/page/year: 18,229,1966
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 476 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans
   Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium)  V.4-   
   1898-  Volume(issue)/page/year: 145,233,1963
 
                            *** END OF RECORD ***