*** CHEMICAL IDENTIFICATION ***

RTECS NUMBER            : ES6630000
CHEMICAL NAME           : Butyric acid,
                          4-(4-amino-2,5-cyclohexadienyl)-2-(2-(methylamino)-3-
                          methylvaleramido)-
CAS REGISTRY NUMBER     : 21754-03-0
LAST UPDATED            : 199503
DATA ITEMS CITED        : 2
MOLECULAR FORMULA       : C17-H29-N3-O3
MOLECULAR WEIGHT        : 323.49
WISWESSER LINE NOTATION : L6U DUTJ CZ F2YVQMVYM1&Y2&1
COMPOUND DESCRIPTOR     : Drug
                          Natural Product
SYNONYMS/TRADE NAMES :
   *   4-(4-Amino-2,5-cyclohexadienyl)-2-(2-(methylamino)-3-methylvaleramido)bu
     tyric acid
   * Antibiotic msd-235-S3
   * Butanoic acid,  
   N-methyl-L-isoleucyl-gamma-(4-amino-2,5-cyclohexadien-1-yl)-L-alpha-amin  
   o-, (E)
   * Butanoic acid,  
   N-methyl-L-isoleucyl-4-(4-amino-2,5-cyclohexadien-1-yl)-L-amino-, trans-
   * 2,5-Cyclohexadiene-1-butyric acid,  
   4-amino-alpha-(3-methyl-2-(methylamino)valeramido)-
   * MSD-235-S3
   * Stravidin-S3
 
                       *** HEALTH HAZARD DATA ***
 
                        ** ACUTE TOXICITY DATA **
 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   85GDA2 "CRC Handbook of Antibiotic Compounds," Vols.1- ,  Berdy, J., Boca
   Raton, FL, CRC Press, 1980-  Volume(issue)/page/year: 4(1),219,1980
 
TYPE OF TEST            : LD - Lethal dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : >320 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JANTAJ Journal of Antibiotics.  (Japan Antibiotics Research Assoc., 2-20-8
   Kamiosaki, Shinagawa-ku, Tokyo, 141, Japan)  V.2-5, 1948-52;  V.21- 1968-
   Volume(issue)/page/year: 38,312,1985
 
                            *** END OF RECORD ***